Description

1-(Cyclobutylcarbonyl)Piperazine HCl is a high-purity, advanced pharmaceutical intermediate of significant interest in modern medicinal chemistry. This compound is valued for its role as a key building block in the synthesis of novel, biologically active molecules, particularly for central nervous system (CNS) and other therapeutic targets. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the development and scale-up manufacturing processes for potential Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Development: Can be utilized for the creation of chemical probes and bioconjugates for biochemical and pharmacological research.
• Custom Synthesis Building Block: Employed by fine chemical suppliers for the custom synthesis of more complex, specialized compounds for client projects.

Basic Information

Product Name	1-(Cyclobutylcarbonyl)Piperazine HCl
CAS No.	1428443-87-1
Molecular Formula	C9H17ClN2O
Molecular Weight	204.70 g/mol
Synonyms	1-(Cyclobutanecarbonyl)piperazine hydrochloride; Piperazine, 1-(cyclobutanecarbonyl)-, hydrochloride; Cyclobutanecarboxylic acid piperazide hydrochloride; N-(Piperazin-1-yl)cyclobutanecarboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Cyclobutylcarbonyl)Piperazine HCl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.