Description

Tau Peptide (294-305) (Human) is a synthetic peptide fragment corresponding to amino acids 294-305 of the human microtubule-associated protein tau. This specific sequence is of significant interest in neuroscience and pharmaceutical research for studying tau protein function, aggregation, and related pathologies. It serves as a critical research tool for academic institutions, diagnostic developers, and biopharmaceutical companies focused on neurodegenerative diseases. The compound is supplied as a high-purity material suitable for demanding biochemical and cell-based applications.

Application

• Neuroscience Research: Fundamental studies on tau protein biology, including its interaction with microtubules and other binding partners.
• Antibody Development & Epitope Mapping: Used as an antigen for the generation and characterization of monoclonal and polyclonal antibodies targeting the tau protein.
• Diagnostic Assay Development: Serves as a key component in the development of immunoassays (ELISA, Western Blot) for detecting tau protein or specific phospho-epitopes.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify compounds that modulate tau aggregation or protein-protein interactions.
• Biomarker Studies: Research into tau-derived peptides as potential biomarkers for Alzheimer's disease and other tauopathies.
• Structural Biology: Utilized in NMR, X-ray crystallography, and other techniques to determine the three-dimensional structure of tau protein regions.

Basic Information

Product Name	Tau Peptide (294-305) (Human)
CAS No.	1428135-29-8
Molecular Formula	C58H95N19O19
Molecular Weight	1322.5 g/mol
Synonyms	Tau (294-305) human; Tau protein (294-305); H-TKSPGSPGTPGSR-OH; Microtubule-associated protein tau (294-305); Tau peptide fragment 294-305; Alzheimer's disease tau peptide; PHF-tau related peptide; Neurofibrillary tangle tau peptide
EINECS	Contact for details

Quality Control

Our Tau Peptide (294-305) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Standard quality control includes HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ±10% of theoretical
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or dilute acetic acid
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.