Description

5-Bromo-1,2,4-Triazole-3-Carbonitrile is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive bromine and nitrile functional groups. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures, including potential kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the triazole core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of novel polymers, dyes, and photoactive materials with specific electronic properties.
• Chemical Biology Probes: Useful for designing molecular probes and tags to study biological processes and enzyme functions.

Basic Information

Product Name	5-Bromo-1,2,4-Triazole-3-Carbonitrile
CAS No.	1427475-12-4
Molecular Formula	C3HBrN4
Molecular Weight	172.97 g/mol
Synonyms	5-Bromo-1H-1,2,4-triazole-3-carbonitrile; 3-Cyano-5-bromo-1,2,4-triazole; 5-Bromo-3-cyano-1,2,4-triazole; 1,2,4-Triazole-3-carbonitrile, 5-bromo-; 5-Bromo-1,2,4-triazole-3-carbonitrile; 1427475-12-4
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,4-Triazole-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.