Description

Cefsulodin Sodium Salt Hydrate is a semi-synthetic, β-lactamase-resistant cephalosporin antibiotic. It is valued for its potent and specific activity against Pseudomonas aeruginosa, making it a critical tool in microbiological research and quality control. This compound is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions for susceptibility testing, media supplementation, and antimicrobial studies.

Application

• Microbiological Assay Standard: Used as a reference standard in agar diffusion and broth dilution methods to determine antibiotic potency and microbial susceptibility.
• Selective Culture Media: Incorporated into agar plates for the selective isolation and identification of specific bacterial strains, particularly in clinical diagnostics.
• Pharmaceutical Research: Serves as a key intermediate or active pharmaceutical ingredient (API) in R&D for novel anti-pseudomonal formulations.
• Quality Control Testing: Employed in pharmaceutical and biotech QC labs for sterility testing, antimicrobial effectiveness testing (AET), and preservative challenge tests.
• Veterinary Medicine: Applied in research for developing treatments for bacterial infections in animals.
• Academic & Clinical Studies: Used to study bacterial resistance mechanisms, pharmacokinetics, and the efficacy of combination therapies.

Basic Information

Product Name	Cefsulodin Sodium Salt Hydrate
CAS No.	1426397-23-0
Molecular Formula	C22H19N4NaO8S2 · xH2O
Molecular Weight	554.53 g/mol (anhydrous basis)
Synonyms	Cefsulodin Sodium; Sodium Cefsulodin; Cefsulodin Sodium Hydrate; SCE-129; (6R,7R)-7-[(R)-2-(4-Carbamoyl-2-thienyl)acetamido]-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; Antibiotic SCE-129; 3-[(4-Carbamoylpyridinio)methyl]-7-(2-(2-thienyl)acetamido)ceph-3-em-4-carboxylate Sodium Salt
EINECS	Contact for details

Quality Control

Our Cefsulodin Sodium Salt Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light may lead to degradation. For long-term storage, consider desiccant and under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0%
pH (1% Solution)	4.5 - 6.5
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Microbial Enumeration	≤ 1000 CFU/g
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.