Description

Norhydrocodone-D3 is a deuterium-labeled internal standard of the opioid metabolite norhydrocodone, essential for precise analytical quantification. This high-purity reference material is critical for ensuring accuracy and reliability in forensic, clinical, and pharmaceutical research. It is primarily utilized by analytical laboratories, forensic toxicologists, and pharmaceutical developers for applications such as drug metabolism studies, pharmacokinetic research, and compliance testing.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the accurate quantification of norhydrocodone and related opioids in biological matrices.
• Forensic Toxicology: Essential for confirmatory testing and method development in workplace drug testing, post-mortem analysis, and DUI cases.
• Clinical Research: Supports pharmacokinetic and pharmacodynamic studies to understand drug metabolism, bioavailability, and elimination profiles.
• Pharmaceutical Development: Aids in the bioanalysis phase of drug development for opioid-based medications and their metabolites.
• Reference Material: Serves as a certified reference standard for calibrating laboratory equipment and validating analytical methods.
• Regulatory Compliance Testing: Used in laboratories to ensure compliance with FDA, SAMHSA, or other international regulatory guidelines for opioid testing.

Basic Information

Product Name	Norhydrocodone-D3
CAS No.	1426215-53-3
Molecular Formula	C18H18D3NO3
Molecular Weight	302.39 g/mol
Synonyms	Norhydrocodone-d3; 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-one-d3; 17-Methyl-3-methoxy-4,5α-epoxymorphinan-6-one-d3; Dihydrocodeinone Impurity D-d3; Deuterated Norhydrocodone; Norhydrocodone (D3); Norhydrocodone-d3 Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Norhydrocodone-D3 is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for reference materials. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and analytical results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.