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Ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(Ent-[Amyloid β-Protein (16-20)]) CAS NO 1426174-31-3


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CAS No.:1426174-31-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(Ent-[Amyloid β-Protein (16-20)]) is a synthetic, retro-inverso peptide derivative designed for advanced biochemical and pharmaceutical research. This compound is of significant interest for its potential role in studying amyloid-beta protein aggregation mechanisms and related neurodegenerative pathways. It serves as a critical research tool for scientists and developers in neuroscience, drug discovery, and diagnostic assay development, particularly for Alzheimer's disease research.

Application

  • Biochemical Research: Used as a model compound to study the aggregation kinetics and inhibition of amyloid-beta peptides.
  • Drug Discovery: Serves as a key intermediate or reference standard in the development of novel therapeutics targeting amyloidosis.
  • Diagnostic Development: Employed in the research and validation of diagnostic assays and imaging agents for detecting amyloid plaques.
  • Neuroscience Studies: Utilized in vitro and in vivo studies to investigate the pathophysiology of neurodegenerative diseases.
  • Peptide Chemistry: Acts as a specialized building block or reference material in peptide synthesis and structural analysis.
  • Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies on protein misfolding and neurotoxicity.

Basic Information

Item Details
Product Name Ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(Ent-[Amyloid β-Protein (16-20)])
CAS No. 1426174-31-3
Molecular Formula Contact for details
Molecular Weight Contact for details
Synonyms Ent-[Aβ (20-16)]-β-Ala-D-Lys(Ent-[Aβ (16-20)]); Retro-inverso Amyloid-β (16-20) derivative; RI-Amyloid β-Protein fragment; D-amino acid amyloid beta peptide analog; Aβ (16-20) retro-inverso peptide; Research peptide 1426174-31-3
EINECS Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade peptides. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation (by MS), and other critical parameters are available upon request. We adhere to stringent in-house quality protocols to support reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, store at 2-8°C.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC & MS) Conforms to reference standard
Purity (HPLC) ≥ 95%
Single Impurity (HPLC) ≤ 1.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80%
Solubility Soluble in DMSO, Acetic Acid; Sparingly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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