Description

Norhydrocodone-D3 Hydrochloride Solution is a high-purity, isotopically labeled internal standard critical for modern analytical workflows. This deuterated compound is essential for ensuring the accuracy and reliability of quantitative analyses in regulated environments. It is primarily utilized by pharmaceutical research laboratories, forensic toxicology departments, and contract research organizations (CROs) for method development and validation.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the precise quantification of Norhydrocodone and related opiate metabolites in biological matrices (e.g., urine, plasma, serum).
• Forensic Toxicology: Critical for confirmatory testing and method validation in workplace drug testing, post-mortem analysis, and clinical toxicology.
• Pharmacokinetic Studies: Enables accurate measurement of drug metabolite levels in absorption, distribution, metabolism, and excretion (ADME) research.
• Pharmaceutical R&D: Supports drug metabolism studies, bioanalytical method development, and quality control for active pharmaceutical ingredients (APIs).
• Reference Material: Serves as a certified reference material (CRM) for calibrating instruments and ensuring analytical method compliance with FDA, SAMHSA, or other regulatory guidelines.

Basic Information

Product Name	Norhydrocodone-D3 Hydrochloride Solution
CAS No.	1426173-17-2
Molecular Formula	C17H18D3ClNO4
Molecular Weight	Contact for details
Synonyms	17-Norhydrocodone-D3 HCl; 6-Deoxy-6-norhydrocodone-D3 hydrochloride; Norhydrocodone-d3 (hydrochloride); 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-one-17,17,18-d3 hydrochloride; Deuterated Norhydrocodone HCl; Norhydrocodone Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Norhydrocodone-D3 Hydrochloride Solution is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for isotopic purity and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at the recommended temperature as specified on the Certificate of Analysis, typically between 2°C and 8°C for solutions. Keep away from strong acids and organic solvents. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95% (by area)
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98%
Solvent	Methanol, Acetonitrile, or as specified
Concentration	100 µg/mL, 1.0 mg/mL, or as customized

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.