Description

Tat-Beclin 1 Peptide is a cell-penetrating peptide construct designed to induce autophagy, a critical cellular recycling and degradation process. This compound matters for researchers and developers targeting neurodegenerative diseases, cancer, and infectious diseases where modulating autophagy pathways is a promising therapeutic strategy. It is primarily needed by biotechnology and pharmaceutical R&D teams, as well as academic research institutions focused on cell biology, neurobiology, and oncology.

Application

• Autophagy Research: A key tool for studying the molecular mechanisms and regulation of autophagy in various cell types.
• Neurodegenerative Disease Models: Investigation of therapeutic potential in conditions like Alzheimer's, Parkinson's, and Huntington's disease.
• Oncology Research: Exploring the role of autophagy in cancer cell survival, death, and response to chemotherapy.
• Infectious Disease Studies: Research into host-pathogen interactions, as autophagy can eliminate intracellular microbes.
• Cardiovascular Research: Studying autophagy's protective role in cardiac cells under stress conditions like ischemia.
• Metabolic Disorder Studies: Investigating links between autophagy, metabolism, and diseases such as diabetes.
• Drug Discovery Screening: Used as a reference compound or positive control in high-throughput assays for autophagy modulators.
• Preclinical Development: Evaluation of efficacy and mechanism of action in animal models of relevant diseases.

Basic Information

Item	Details
Product Name	Tat-Beclin 1 Peptide
CAS No.	1423821-88-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TatBeclin 1; TAT-Beclin 1; Tat-Beclin1; Cell-Penetrating Autophagy-Inducing Peptide; HIV-1 TAT/Beclin 1-derived Peptide; Autophagy-Inducing Peptide; Beclin 1-Derived Peptide; Tat-Beclin 1 (1-15); Tat-BECN1
EINECS	Contact for details

Quality Control

Our Tat-Beclin 1 Peptide is manufactured under strict quality systems suitable for research use. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.