Description

n-Isopropyl L-Z-Isoleucinamide is a specialized chiral amino acid derivative designed for advanced chemical synthesis. This high-purity building block is critical for researchers and manufacturers requiring precise stereochemistry and functional group compatibility. It is primarily utilized in the pharmaceutical and biotechnology sectors for applications such as peptide synthesis and medicinal chemistry research.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce the L-isoleucine moiety.
• Medicinal Chemistry & Drug Discovery: Serves as a crucial building block for constructing compound libraries and optimizing lead molecules for improved pharmacokinetic properties.
• Bioconjugation: Facilitates the site-specific modification of proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
• Chemical Biology Research: Employed in the study of enzyme mechanisms, protein-protein interactions, and metabolic pathways.
• Catalyst and Ligand Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	n-Isopropyl L-Z-Isoleucinamide
CAS No.	1423037-44-8
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	L-Isoleucine, N-(1-methylethyl)-, amide; (2S,3S)-2-Amino-3-methyl-N-(propan-2-yl)pentanamide; N-Isopropyl-L-isoleucinamide; L-Z-Isoleucine N-isopropylamide; (2S,3S)-2-Amino-N-isopropyl-3-methylpentanamide; Isoleucinamide, N-isopropyl-, L-; Z-L-Isoleucine isopropylamide
EINECS	Contact for details

Quality Control

Our n-Isopropyl L-Z-Isoleucinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.