Description

Octyl-β-D-Glucuronide Methyl Ester is a high-purity biochemical reference standard and synthetic intermediate. This compound is critical for analytical method development and validation, particularly in the field of drug metabolism and pharmacokinetics (DMPK). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of diagnostic reagents for precise quantification and research.

Application

• Biochemical Research Standard: Serves as a primary reference material for calibrating analytical instruments in metabolic studies.
• Drug Metabolism & Pharmacokinetics (DMPK): Used as a standard for the identification and quantification of glucuronide metabolites in in vitro and in vivo assays.
• Enzyme Substrate/Inhibitor Studies: Acts as a substrate for UDP-glucuronosyltransferase (UGT) enzymes to study glucuronidation pathways.
• Diagnostic Reagent Manufacturing: Employed in the synthesis and quality control of diagnostic kits targeting specific metabolic biomarkers.
• Pharmaceutical Impurity Profiling: Used as a marker to identify and control related substances in drug substance and product analysis.
• Academic Research: Facilitates studies in biochemistry, enzymology, and medicinal chemistry related to phase II drug metabolism.

Basic Information

Item	Details
Product Name	Octyl-β-D-Glucuronide Methyl Ester
CAS No.	1423035-40-8
Molecular Formula	C₁₅H₂₈O₈
Molecular Weight	336.38 g/mol
Synonyms	Methyl Octyl β-D-Glucopyranosiduronate; Octyl β-D-Glucopyranosiduronic Acid Methyl Ester; 1-Octyl β-D-Glucuronide Methyl Ester; Methyl (Octyl β-D-Glucopyranosid)uronate; Octyl Glucuronide Methyl Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Octyl-β-D-Glucuronide Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.