Description

(3As,8As)-(+)-4,4,8,8-Tetrakis(3,5-Di-I-Propylphenyl)Tetrahydro-2,2-Dimethyl-6-Phenyl-1,3-Dioxolo[4,5-E]Dioxaphosphepin is a sophisticated, chiral organophosphorus compound featuring a unique dioxaphosphepin core structure. This compound matters as a high-value, specialized ligand or catalyst precursor, offering precise stereochemical control in asymmetric synthesis for advanced pharmaceutical and fine chemical manufacturing. It is essential for R&D chemists and process development scientists working on novel synthetic routes, particularly in the production of active pharmaceutical ingredients (APIs) and complex organic molecules where enantioselectivity is critical.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in enantioselective hydrogenation, cross-coupling, and other C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereocontrolled synthesis of complex chiral intermediates for novel drug candidates and APIs.
• Advanced Material Research: Used in the development of chiral polymers or materials with specific optical properties.
• Methodology Development: A key reagent in academic and industrial research for developing new catalytic asymmetric transformations.
• Fine Chemical Production: Facilitating the commercial-scale synthesis of enantiomerically pure flavors, fragrances, and agrochemicals.

Basic Information

Item	Details
Product Name	(3As,8As)-(+)-4,4,8,8-Tetrakis(3,5-Di-I-Propylphenyl)Tetrahydro-2,2-Dimethyl-6-Phenyl-1,3-Dioxolo[4,5-E]Dioxaphosphepin
CAS No.	1422371-27-4
Molecular Formula	C58H72IO4P
Molecular Weight	1014.97 g/mol
Synonyms	(+)-Tetrahydro-2,2-dimethyl-6-phenyl-4,4,8,8-tetrakis(3,5-diisopropylphenyl)-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin; Chiral Dioxaphosphepin Ligand; (3As,8As)-(+)-Dioxaphosphepin Derivative; CAS 1422371-27-4; Phosphorus Heterocycle Ligand; Asymmetric Catalyst Precursor; P,O-Bidentate Ligand
EINECS	Contact for details

Quality Control

Every batch of our (3As,8As)-(+)-4,4,8,8-Tetrakis(3,5-Di-I-Propylphenyl)Tetrahydro-2,2-Dimethyl-6-Phenyl-1,3-Dioxolo[4,5-E]Dioxaphosphepin undergoes rigorous analytical characterization to ensure high chiral purity and chemical integrity, critical for reproducible performance in sensitive asymmetric reactions. Our quality protocols include advanced techniques like chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.