Description

Rel-(3As,6Ar)-2-Methylhexahydropyrrolo[3,4-C]Pyrrol-1(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined bicyclic pyrrolidine structure. This compound is critical for enabling the synthesis of sophisticated active pharmaceutical ingredients (APIs) with precise three-dimensional configurations. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Reagent: Used in advanced medicinal chemistry for constructing constrained, nitrogen-rich heterocyclic scaffolds essential for drug discovery.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems for stereoselective transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function and receptor interactions within biological systems.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	Rel-(3As,6Ar)-2-Methylhexahydropyrrolo[3,4-C]Pyrrol-1(2H)-One
CAS No.	1422134-66-4
Molecular Formula	C8H14N2O
Molecular Weight	154.21 g/mol
Synonyms	2-Methylhexahydro-1H-pyrrolo[3,4-c]pyrrol-1-one (rel-(3aR,6aR)-); (3aR,6aR)-2-Methyloctahydropyrrolo[3,4-c]pyrrol-1-one; (3aR,6aR)-2-Methylhexahydro-1H-pyrrolo[3,4-c]pyrrol-1-one; 1(2H)-Pyrrolone, hexahydro-2-methyl-, (3aR,6aR)-rel-; Bicyclic Pyrrolidone Derivative; Advanced Pyrrolidine Intermediate; Chiral Lactam Building Block
EINECS	Contact for details

Quality Control

Every batch of Rel-(3As,6Ar)-2-Methylhexahydropyrrolo[3,4-C]Pyrrol-1(2H)-One is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results from techniques including HPLC, GC, NMR, and chiral analysis to confirm stereochemical purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.