Description

Propargyl-Peg8-Alcohol is a high-purity, functionalized polyethylene glycol derivative featuring a terminal propargyl group. This compound is a critical building block in click chemistry, enabling efficient and selective conjugation reactions under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical, biotech, and materials science industries developing advanced drug delivery systems, bioconjugates, and functional polymers.

Application

• Bioconjugation and Click Chemistry: Serves as a key linker for attaching drugs, peptides, or fluorescent dyes to biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Pharmaceutical Development: Used to create PEGylated prodrugs and therapeutic agents to enhance solubility, stability, and pharmacokinetic profiles.
• Polymer Synthesis: Acts as a functional initiator or monomer for synthesizing smart polymers, hydrogels, and surface coatings with tailored properties.
• Diagnostic Reagents: Employed in the development of diagnostic assays and imaging probes for targeted detection.
• Material Science: Facilitates the surface functionalization of nanoparticles and other nanomaterials for specialized applications.
• Chemical Biology: A versatile tool for labeling and studying biomolecular interactions in research settings.

Basic Information

Product Name	Propargyl-Peg8-Alcohol
CAS No.	1422023-54-8
Molecular Formula	C19H36O9
Molecular Weight	408.49 g/mol
Synonyms	Propargyl-PEG8-OH; 2,5,8,11,14,17,20,23-Octaoxapentacos-24-yn-1-ol; 3-(2,5,8,11,14,17,20,23-Octaoxapentacos-24-yn-1-yloxy)propan-1-ol; Propargyl octaethylene glycol; Propargyl-PEG8-alcohol; 8-Amino-3,6-dioxaoctyl propargyl ether; Propargyl-PEG8; Alkyne-PEG8-OH
EINECS	Contact for details

Quality Control

Our Propargyl-Peg8-Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.