Description

tert-Butyl 1-Cyano-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate CAS NO 1421940-05-7 is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of complex, bioactive molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential neurological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs targeting novel biological pathways.
• Protease Inhibitor Development: Used in the research and synthesis of potential inhibitors for various protease enzymes.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes to study enzyme function and protein interactions.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of candidate drugs.
• Academic Research: Applied in university and institutional labs for methodological studies in heterocyclic and strained ring chemistry.

Basic Information

Product Name	tert-Butyl 1-Cyano-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate
CAS No.	1421940-05-7
Molecular Formula	C12H18N2O2
Molecular Weight	222.28 g/mol
Synonyms	1-Cyano-3-azabicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester; tert-Butyl 1-cyano-3-azabicyclo[3.1.0]hexane-3-carboxylate; 3-Boc-1-cyano-3-azabicyclo[3.1.0]hexane; 3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 1-cyano-, 1,1-dimethylethyl ester; 1-Cyano-3-azabicyclo[3.1.0]hexane-3-carboxylic acid 1,1-dimethylethyl ester; Bicyclo[3.1.0]hexane intermediate; 3-Boc-1-CN-3-azabicyclo[3.1.0]hexane
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Cyano-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.