Description

4-Amino-1-(Trifluoromethyl)Cyclohexanol Hydrochloride is a high-value, functionalized cyclohexane derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining an amino group, a trifluoromethyl group, and a hydroxyl moiety, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, where its trifluoromethyl group can significantly enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for functionalized cyclohexane units in the synthesis of high-performance liquid crystal compounds for display technologies.
• Advanced Material Science: Building block for specialty polymers and coatings that require specific chemical resistance and stability.
• Organic Synthesis Research: A valuable reagent in academic and industrial laboratories for methodological studies and the construction of complex molecular architectures.

Basic Information

Product Name	4-Amino-1-(Trifluoromethyl)Cyclohexanol Hydrochloride
CAS No.	1421602-78-9
Molecular Formula	C7H11F3NO • HCl
Molecular Weight	221.62 g/mol (Free base: 185.16 g/mol)
Synonyms	4-Amino-1-(trifluoromethyl)cyclohexan-1-ol hydrochloride; 1-(Trifluoromethyl)-4-aminocyclohexanol HCl; 4-Amino-α-(trifluoromethyl)cyclohexanemethanol hydrochloride; (4-Aminocyclohexyl)(trifluoromethyl)methanol hydrochloride; 4-Amino-1-trifluoromethyl-cyclohexanol hydrochloride; 4-Amino-α-(trifluoromethyl)cyclohexanemethanol hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-1-(Trifluoromethyl)Cyclohexanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of our clients in regulated industries. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.