Description

tert-Butyl 3-(1-Aminoethyl)Azetidine-1-Carboxylate is a high-purity, protected azetidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile, nitrogen-containing scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Development: Used in constructing advanced active ingredients for crop protection products.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The azetidine ring is a valuable bioisostere for peptide bonds and other functional groups in medicinal chemistry.
• Chemical Biology Probes: Utilized in the development of tool compounds and molecular probes for biological target validation.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects requiring a protected amino-azetidine moiety.

Basic Information

Product Name	tert-Butyl 3-(1-Aminoethyl)Azetidine-1-Carboxylate
CAS No.	1420852-13-6
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-Boc-3-(1-aminoethyl)azetidine; tert-Butyl 3-(1-aminoethyl)azetidine-1-carboxylate; 3-(1-Aminoethyl)-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-(1-aminoethyl)-1-azetidinecarboxylate; 3-(1-Aminoethyl)azetidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-(α-aminoethyl)azetidine; (1-(tert-Butoxycarbonyl)azetidin-3-yl)(ethyl)amine (tautomeric form); Boc-Azetidine-(1-aminoethyl) derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(1-Aminoethyl)Azetidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.