Description

3-Oxetanecarbonitrile is a versatile heterocyclic nitrile building block, essential for advanced organic synthesis and pharmaceutical research. Its strained oxetane ring and reactive nitrile group make it a valuable precursor for constructing complex molecular architectures. This high-purity intermediate is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its oxetane moiety to modulate biological activity and physicochemical properties.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and high-performance materials with tailored thermal and mechanical characteristics.
• Chemical Biology Probe Development: Employed in the creation of labeled compounds and molecular probes for studying biological pathways and enzyme mechanisms.
• Ligand and Catalyst Design: Utilized in organometallic chemistry and catalysis research to construct novel ligand frameworks for transition metal complexes.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis, including ring-opening reactions and cycloadditions.

Basic Information

Product Name	3-Oxetanecarbonitrile
CAS No.	1420800-16-3
Molecular Formula	C4H5NO
Molecular Weight	83.09 g/mol
Synonyms	Oxetane-3-carbonitrile; 3-Cyanooxetane; Oxetan-3-yl cyanide; 3-Oxetanylcarbonitrile; Oxetane-3-carbonitrile (9CI); 1-Oxa-2-cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Oxetanecarbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical properties. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. Due to its reactivity profile, it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	To be provided on COA
Density	To be provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.