Description

2,4-Difluoro-5-Bromophenylboronic Acid Piancol Ester is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in its dual functionality, serving as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions to construct complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical synthon for constructing complex drug candidates, especially in the synthesis of fluorinated and brominated heterocycles and biaryl compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro and bromo substituents can enhance biological activity and environmental stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory organic synthesis.

Basic Information

Product Name	2,4-Difluoro-5-Bromophenylboronic Acid Piancol Ester
CAS No.	1419602-18-8
Molecular Formula	C13H17BBrF2O3
Molecular Weight	341.99 g/mol
Synonyms	5-Bromo-2,4-difluorophenylboronic acid Piancol ester; 2,4-Difluoro-5-bromobenzeneboronic acid Piancol ester; (5-Bromo-2,4-difluorophenyl)boronic acid pinacol ester; Pinacol (5-bromo-2,4-difluorophenyl)boronate; 2,4-Difluoro-5-bromophenylboronic acid pinacol ester; 5-Bromo-2,4-difluorophenyl-Bpin; CAS 1419602-18-8
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Bromophenylboronic Acid Piancol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and production needs with reliable, traceable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.