Description

tert-Butyl 4-Hydroxy-Octahydrocyclopenta[B]Pyrrole-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, functionalized bicyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of active pharmaceutical ingredients, especially those containing fused pyrrolidine or proline-like motifs.
• Chemical Biology Probes: Employed in the development of specialized molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	tert-Butyl 4-Hydroxy-Octahydrocyclopenta[B]Pyrrole-1-Carboxylate
CAS No.	1419101-37-3
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	1-Boc-4-hydroxyoctahydrocyclopenta[b]pyrrole; tert-Butyl 4-hydroxy-2,3,3a,4,5,6-hexahydro-1H-cyclopenta[b]pyrrole-1-carboxylate; 4-Hydroxyoctahydrocyclopenta[b]pyrrole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-hydroxyoctahydrocyclopenta[b]pyrrole; (3aR,4S)-rel-1,2,3,3a,4,5,6,6a-Octahydrocyclopenta[b]pyrrol-4-ol 1-carboxylic acid 1,1-dimethylethyl ester; BOC-4-Hydroxyoctahydrocyclopenta[b]pyrrole
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Hydroxy-Octahydrocyclopenta[B]Pyrrole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP (current Good Manufacturing Practice) starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.