Description

2-Fluoro-6-Aminophenylboronic Acid Pinacol Ester is a high-purity, multifunctional boronic ester building block essential for modern synthetic chemistry. This compound is specifically designed for use in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is paramount.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic scaffolds.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where its boronic ester group facilitates polymerization and conjugation.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors for studying biological processes, leveraging the orthogonal reactivity of the amine and boronate groups.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-Fluoro-6-Aminophenylboronic Acid Pinacol Ester
CAS No.	1418130-40-1
Molecular Formula	C₁₂H₁₇BFNO₂
Molecular Weight	237.08 g/mol
Synonyms	2-Amino-3-fluorophenylboronic acid pinacol ester; (2-Amino-3-fluorophenyl)boronic acid pinacol ester; 3-Fluoro-2-aminophenylboronic acid pinacol ester; B-(2-Amino-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Fluoro-6-aminobenzeneboronic acid pinacol ester; PINACOL 2-AMINO-3-FLUOROBENZENEBORONATE; 1418130-40-1
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Aminophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.