Description

1-(Cyclopentylcarbonyl)Proline is a specialized proline derivative featuring a cyclopentylcarbonyl moiety, serving as a critical chiral building block and intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and bioactive compounds. Pharmaceutical researchers, agrochemical developers, and fine chemical manufacturers need it for applications in medicinal chemistry, peptide mimetics, and as a precursor for sophisticated chemical libraries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other targeted therapies.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational constraints and modify the pharmacokinetic properties of peptide-based compounds.
• Agrochemical Synthesis: Serves as a building block for creating novel, high-efficacy active ingredients with specific stereochemical requirements.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of novel chiral ligands for asymmetric catalytic reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-(Cyclopentylcarbonyl)Proline
CAS No.	1417985-23-9
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	L-Proline, 1-(cyclopentylcarbonyl)-; (S)-1-(Cyclopentanecarbonyl)pyrrolidine-2-carboxylic acid; 1-Cyclopentanecarbonyl-L-proline; Cyclopentanecarboxylic acid (S)-1-(2-carboxy-pyrrolidin-1-yl)-methanone; 1-(Cyclopentanoyl)-L-proline; N-(Cyclopentylcarbonyl)-L-proline; 1-Cyclopentylcarbonyl-L-proline; 1417985-23-9
EINECS	Contact for details

Quality Control

Our 1-(Cyclopentylcarbonyl)Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.