Description

(2E)-2-(2,4-Difluorophenyl)But-2-Enenitrile is a specialized fluorinated organic nitrile building block. This compound is valued for its unique molecular scaffold, which incorporates both a nitrile functional group and a difluorophenyl moiety, making it a versatile intermediate in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Synthesis Reagent: Employed in organic chemistry research for constructing complex molecules via reactions such as cycloadditions or nucleophilic additions to the nitrile group.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	(2E)-2-(2,4-Difluorophenyl)But-2-Enenitrile
CAS No.	1417644-30-4
Molecular Formula	C10H7F2N
Molecular Weight	179.17 g/mol
Synonyms	(E)-2-(2,4-Difluorophenyl)but-2-enenitrile; 2-(2,4-Difluorophenyl)-2-butenenitrile; (2E)-2-(2,4-Difluorophenyl)-2-butenenitrile; 2,4-Difluoro-α-methylcinnamonitrile; But-2-enenitrile, 2-(2,4-difluorophenyl)-, (2E)-; 1417644-30-4
EINECS	Contact for details

Quality Control

Our (2E)-2-(2,4-Difluorophenyl)But-2-Enenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee supply reliability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.