Description

1-Bromo-2-Chloro-3-(Trifluoromethoxy)Benzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in the development of active pharmaceutical ingredients (APIs) with trifluoromethoxy or halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and trifluoromethoxy groups confer desirable biological activity and stability.
• Material Science: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials requiring specific halogenated aromatic structures.
• Chemical Research & Development: A versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing complex functionalities into molecular scaffolds.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of specialized halogenated dyes and pigments.

Basic Information

Product Name	1-Bromo-2-Chloro-3-(Trifluoromethoxy)Benzene
CAS No.	1417568-88-7
Molecular Formula	C7H3BrClF3O
Molecular Weight	275.45 g/mol
Synonyms	2-Chloro-1-bromo-3-(trifluoromethoxy)benzene; 3-Bromo-2-chloro-1-(trifluoromethoxy)benzene; Benzene, 1-bromo-2-chloro-3-(trifluoromethoxy)-; 1-Bromo-2-chloro-3-(trifluoromethoxy)benzene; 2-Chloro-3-(trifluoromethoxy)bromobenzene; 3-(Trifluoromethoxy)-1-bromo-2-chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-3-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.