Description

1-Bromo-3-Chloro-5-(Trifluoromethoxy)Benzene is a high-purity, multi-functional halogenated benzene derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering versatile reactivity for introducing specific halogenated aromatic motifs. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the development of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Employed to introduce halogenated aromatic groups into polymer chains, modifying thermal stability, flame retardancy, and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to construct complex biaryl systems.
• Material Science Research: Utilized in academic and industrial R&D for creating novel organic frameworks, ligands for catalysis, and advanced functional materials.

Basic Information

Product Name	1-Bromo-3-Chloro-5-(Trifluoromethoxy)Benzene
CAS No.	1417567-41-9
Molecular Formula	C7H3BrClF3O
Molecular Weight	290.45 g/mol
Synonyms	3-Bromo-5-Chloro-1-(Trifluoromethoxy)Benzene; 5-Bromo-3-Chloro-1-(Trifluoromethoxy)Benzene; Benzene, 1-bromo-3-chloro-5-(trifluoromethoxy)-; 1-(Trifluoromethoxy)-3-bromo-5-chlorobenzene; 3-Chloro-5-bromo-1-(trifluoromethoxy)benzene; 1-Bromo-3-chloro-5-(trifluoromethoxy)benzene; 5-Chloro-3-bromo-1-(trifluoromethoxy)benzene; BCTFB (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-5-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.