Description

4-Methanesulfonyl-3-(Trifluoromethyl)Phenyl]Boronic Acid CAS NO 1417301-54-2 is a high-value, organoboron building block characterized by its unique trifluoromethyl and methanesulfonyl substituents. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for creating complex carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Key intermediate in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds.
• Critical building block for pharmaceutical research and development, particularly in creating drug candidates with enhanced metabolic stability and bioavailability.
• Used in the synthesis of agrochemicals, such as herbicides and fungicides, leveraging the properties of the trifluoromethyl group.
• Precursor for the development of advanced materials, including organic semiconductors and liquid crystals.
• Valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Employed in academic and industrial R&D for methodological development and library synthesis.

Basic Information

Product Name	4-Methanesulfonyl-3-(Trifluoromethyl)Phenyl]Boronic Acid
CAS No.	1417301-54-2
Molecular Formula	C9H8BF3O4S
Molecular Weight	280.03 g/mol
Synonyms	[4-(Methylsulfonyl)-3-(trifluoromethyl)phenyl]boronic acid; 3-Trifluoromethyl-4-methylsulfonylphenylboronic acid; 4-Methanesulfonyl-3-trifluoromethylbenzeneboronic acid; (4-Methanesulfonyl-3-trifluoromethylphenyl)boronic acid; Boronic acid, B-[4-(methylsulfonyl)-3-(trifluoromethyl)phenyl]-; 4-Methylsulfonyl-3-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Methanesulfonyl-3-(Trifluoromethyl)Phenyl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.