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2-Amino-6-Fluorophenylboronic Acid CAS NO 1417200-93-1


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CAS No.:1417200-93-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-6-Fluorophenylboronic Acid is a specialized bifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of an aromatic amine and a boronic acid group on a fluorinated benzene ring, enabling precise cross-coupling reactions and molecular assembly. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds, particularly for applications in medicinal chemistry and material science.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
  • Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for constructing biaryl and heterobiaryl structures, a cornerstone of modern medicinal chemistry.
  • Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides with improved efficacy and selectivity.
  • Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
  • Chemical Biology & Proteomics: Utilized in the development of molecular probes and sensors for studying biological processes and protein interactions.
  • Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name 2-Amino-6-Fluorophenylboronic Acid
CAS No. 1417200-93-1
Molecular Formula C6H7BFNO2
Molecular Weight 154.94 g/mol
Synonyms (2-Amino-6-fluorophenyl)boronic acid; 2-Fluoro-6-aminophenylboronic acid; 6-Fluoro-2-aminobenzeneboronic acid; B-(2-Amino-6-fluorophenyl)boronic acid; 2-Amino-6-fluorobenzeneboronic acid; 1417200-93-1; Boronic acid, B-(2-amino-6-fluorophenyl)-
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Quality Control

Our 2-Amino-6-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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