Description

4-Fluoro-2-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides with enhanced activity and environmental profiles.
• Material Science: Precursor for creating fluorinated polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application, facilitating the efficient formation of biaryl and heterobiaryl structures in complex molecule assembly.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries for screening.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis.

Basic Information

Item	Details
Product Name	4-Fluoro-2-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	1416723-10-8
Molecular Formula	C₁₃H₁₅BF₄O₂
Molecular Weight	290.07 g/mol
Synonyms	4-Fluoro-2-(trifluoromethyl)benzeneboronic acid pinacol ester; (4-Fluoro-2-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-Trifluoromethyl-4-fluorophenylboronic acid pinacol ester; 4-Fluoro-α,α,α-trifluoro-o-tolylboronic acid pinacol ester; Pinacol [4-fluoro-2-(trifluoromethyl)phenyl]boronate; CAS 1416723-10-8
EINECS	Contact for details

Quality Control

Every batch of our 4-Fluoro-2-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency, with comprehensive testing including HPLC assay, NMR confirmation, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.