Description

3-Fluoro-5-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile building block in the research and development of novel drug candidates, particularly those containing fluorinated and methoxylated aromatic systems.
• Agrochemical Active Ingredient Development: Used in the synthesis of advanced herbicides, fungicides, and insecticides where the specific substitution pattern imparts desirable biological activity.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis or as a precursor for functional materials.
• Organic Electronic Materials Research: A potential monomer or intermediate in the creation of conjugated polymers and small molecules for OLEDs or organic semiconductors.
• Chemical Biology & Probe Development: Useful for creating tagged molecules or probes for studying biological systems due to its reactive handle.

Basic Information

Product Name	3-Fluoro-5-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1416367-00-4
Molecular Formula	C₁₃H₁₈BFO₃
Molecular Weight	252.09 g/mol
Synonyms	3-Fluoro-5-methoxyphenylboronic acid pinacol ester; (3-Fluoro-5-methoxyphenyl)boronic acid pinacol ester; 2-(3-Fluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro-5-methoxybenzeneboronic acid pinacol ester; 3-Fluoro-5-methoxy-Benzeneboronic acid pinacol ester; Pinacol (3-fluoro-5-methoxyphenyl)boronate; 1416367-00-4
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.