Description

1-(2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazine CAS NO 1415793-99-5 is a high-value, advanced pharmaceutical intermediate featuring a piperazine ring and a pinacol boronate ester group. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by introducing the fluoro-phenyl-piperazine motif.
• Material Science: Serves as a monomer or precursor for advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and proteomics research due to its reactive boronate ester handle.
• Academic & Contract Research: Utilized in methodological development and discovery chemistry within university and CRO laboratories.

Basic Information

Product Name	1-(2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazine
CAS No.	1415793-99-5
Molecular Formula	C16H24BFN2O2
Molecular Weight	306.19 g/mol
Synonyms	2-(4-(Piperazin-1-yl)-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine; 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpiperazine; 4-(Piperazin-1-yl)-3-fluorophenylboronic acid pinacol ester; 3-Fluoro-4-piperazin-1-ylbenzeneboronic acid pinacol ester; 1415793-99-5; Boronic acid, B-[4-(1-piperazinyl)-3-fluorophenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.