Description

1-Ethynyl-2,3-dihydro-1H-indene is a specialty organic building block featuring a strained fused-ring system with a terminal alkyne functionality, enabling selective C–C bond formation via cross-coupling reactions. It serves as a high-value intermediate for the synthesis of advanced functional materials, including photoactive polymers and pharmaceutical candidates requiring rigid, planar scaffolds. This compound is primarily utilized by R&D chemists and process development teams in fine chemical, agrochemical, and medicinal chemistry sectors where structural precision and coupling efficiency are critical.

Application

• Key intermediate in the synthesis of indene-based conjugated polymers for organic photovoltaics (OPV) and OLED emitters
• Alkyne partner in Sonogashira and Cadiot-Chodkiewicz couplings to construct extended π-systems for optoelectronic materials
• Building block for novel kinase inhibitors and CNS-active compounds leveraging the dihydroindene scaffold’s metabolic stability
• Monomer for thermally stable, high-glass-transition resins used in aerospace composites and microelectronics encapsulation
• Substrate in transition-metal-catalyzed cycloadditions to access polycyclic aromatic hydrocarbons (PAHs) with tailored HOMO/LUMO levels
• Probe molecule in mechanistic studies of alkyne activation pathways on heterogeneous Pd and Ni catalysts

Basic Information

Product Name	1-Ethynyl-2,3-dihydro-1H-indene
CAS No.	1415560-25-6
Molecular Formula	C11H10
Molecular Weight	142.20 g/mol
Synonyms	1-Ethynylindane; 1-Ethynyl-2,3-dihydro-1H-indene; 1-(Ethylnyl)-2,3-dihydro-1H-indene; 1-Ethynyl-2,3-dihydroindene; 1-Ethynylindan; Indane-1-ethyne; 1-Ethynyl-2,3-dihydro-1H-indene (CAS 1415560-25-6); 1-Ethynylindane (97%); 1-Ethynyl-2,3-dihydro-1H-indene, 97%; 1-Ethynylindane, 97%
EINECS	Not listed

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to stringent purity benchmarks appropriate for research-grade and pilot-scale synthetic applications, with full traceability from synthesis through purification and packaging. Testing includes identity confirmation (IR, NMR), assay (HPLC), and impurity profiling (GC-MS) per internal SOPs aligned with ACS and EP guidelines for organic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C under inert atmosphere (nitrogen or argon) to prevent oxidation. Keep away from strong oxidizing agents and sources of ignition. Ensure adequate ventilation in storage areas.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identity (IR)	Conforms to reference spectrum
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	≤2.0% total impurities
Residue on Ignition	≤0.1%
Water (Karl Fischer)	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.