Description

(S)-2,2,2-Trifluoro-n-(1-(4-Formylphenyl)Ethyl)Acetamide is a high-value chiral trifluoroacetamide derivative featuring a formylphenyl group, making it a versatile and critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and fluorinated motifs to modulate the biological activity and physicochemical properties of target molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including potential enzyme inhibitors and receptor ligands.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Employed in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis or as a building block for complex molecular scaffolds in material science.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation or as a core structure in designing fluorescent probes and enzyme inhibitors for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity and fluorinated aromatic systems.

Basic Information

Product Name	(S)-2,2,2-Trifluoro-n-(1-(4-Formylphenyl)Ethyl)Acetamide
CAS No.	1415403-12-1
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	(S)-N-[1-(4-Formylphenyl)ethyl]-2,2,2-trifluoroacetamide; (S)-2,2,2-Trifluoro-N-(1-(4-formylphenyl)ethyl)acetamide; (S)-TFAPA Aldehyde; (S)-α-Methyl-4-formylbenzylamine Trifluoroacetamide; (S)-1-(4-Formylphenyl)ethyl trifluoroacetamide; 1415403-12-1; (S)-Trifluoroacetamide derivative of 1-(4-Formylphenyl)ethylamine
EINECS	Contact for details

Quality Control

Our (S)-2,2,2-Trifluoro-n-(1-(4-Formylphenyl)Ethyl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric excess (ee) and identity confirmation via NMR and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profile, and physical characteristics to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.