Description

3-Fluorocyclobutan-1-One is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a strained cyclobutane ring and a reactive ketone group, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the fluorocyclobutyl moiety to modulate pharmacokinetic properties.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorinated cyclobutane ring can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials with tailored thermal and chemical resistance profiles.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands and organocatalysts for asymmetric synthesis and other specialized chemical transformations.
• Fluorine Chemistry Studies: An important substrate for academic and industrial research exploring new fluorination reactions and the properties of fluorinated alicyclic compounds.

Basic Information

Product Name	3-Fluorocyclobutan-1-One
CAS No.	1415342-84-5
Molecular Formula	C4H5FO
Molecular Weight	88.08 g/mol
Synonyms	3-Fluorocyclobutanone; 3-Fluoro-1-cyclobutanone; 3-Fluorocyclobutyl ketone; 3-Fluorocyclobutan-1-one; 1-Cyclobutanone, 3-fluoro-; 3-Fluorocyclobutanone (CAS 1415342-84-5)
EINECS	Contact for details

Quality Control

Our 3-Fluorocyclobutan-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider maintaining under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.