Description

L-Lysine, N6-(Benzoyloxy)-N2-[(Phenylmethoxy)Carbonyl]-, 1,1-Dimethylethyl Ester is a protected derivative of the essential amino acid L-Lysine, designed for advanced peptide synthesis and pharmaceutical research. This compound matters as a critical building block, offering orthogonal protection of the lysine side chain and α-amino group to enable precise, sequential coupling in complex peptide assembly. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with specific protecting group strategies.
• Solution-Phase Peptide Chemistry: Used in the synthesis of complex peptide sequences where selective deprotection is required.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation and Labeling: The protected functional groups allow for selective modification of peptides for drug delivery systems or diagnostic probes.
• Academic and Industrial Research: A valuable tool for medicinal chemists exploring structure-activity relationships (SAR) in peptide drug discovery.
• Synthesis of Peptidomimetics: Used to create modified peptide structures with enhanced stability or biological activity.

Basic Information

Product Name	L-Lysine, N6-(Benzoyloxy)-N2-[(Phenylmethoxy)Carbonyl]-, 1,1-Dimethyl Ester
CAS No.	1415113-15-3
Molecular Formula	C24H30N2O6
Molecular Weight	442.51 g/mol
Synonyms	N6-Benzoyloxy-N2-[(benzyloxy)carbonyl]-L-lysine tert-butyl ester; Boc-Lys(Z)-OtBu (ambiguous, check context); (2S)-6-[(Benzoyloxy)amino]-2-{[(benzyloxy)carbonyl]amino}hexanoic acid 1,1-dimethylethyl ester; Nα-Cbz-Nε-Bz-L-Lysine tert-Butyl Ester; Z-Lys(Bz)-OtBu; tert-Butyl N6-benzoyloxy-N2-{[(benzyloxy)carbonyl]}-L-lysinate; Protected L-Lysine derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.