Description

Saphris Hydrochloride CAS NO 1412458-61-7 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is critical for ensuring the quality and efficacy of final drug formulations, particularly in the development of neuropsychiatric therapeutics. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the synthesis of advanced active compounds.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) for neuropsychiatric treatments.
• Research and development (R&D) of novel central nervous system (CNS) targeting drugs in academic and industrial laboratories.
• Process development and scale-up activities within pharmaceutical manufacturing.
• Production of reference standards for quality control and analytical method validation.
• Pre-clinical and clinical trial material manufacturing for investigational new drugs.

Basic Information

Product Name	Saphris Hydrochloride
CAS No.	1412458-61-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Asenapine Hydrochloride; (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole hydrochloride; Org 5222 Hydrochloride; SCH 900567; Asenapine HCl
EINECS	Contact for details

Quality Control

Our Saphris Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.