Description

Potassium (2-Acetoxyethyl)Trifluoroborate is an organotrifluoroborate salt, a versatile and stable building block in modern synthetic chemistry. This compound is valued for its role as a robust, air- and moisture-stable precursor to boronic acids, facilitating critical carbon-carbon bond-forming reactions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of biaryl and other C-C bonds, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Manufacturing: Used in the research and scale-up production of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific aryl-alkyl linkages.
• Material Science Research: Serves as a building block for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Peptide Modification and Labeling: Facilitates the site-specific introduction of boron-containing groups into peptides and biomolecules for further functionalization.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis of diverse compound libraries for biological screening.

Basic Information

Product Name	Potassium (2-Acetoxyethyl)Trifluoroborate
CAS No.	1408168-77-3
Molecular Formula	C4H7BF3KO2
Molecular Weight	193.99 g/mol
Synonyms	Potassium 2-Acetoxyethyltrifluoroborate; Potassium Acetoxyethyltrifluoroborate; 2-Acetoxyethyltrifluoroborate Potassium Salt; (2-Acetoxyethyl)trifluoroboronic Acid Potassium Salt; Potassium (Acetoxyethyl)Trifluoroboronate; K-ATE; AcOEt-BF3K
EINECS	Contact for details

Quality Control

Our Potassium (2-Acetoxyethyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) with full batch-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.