Description

6-Boc-2,6-Diazabicyclo[3.2.0]Heptane is a high-value, protected bicyclic diamine intermediate of significant importance in modern pharmaceutical synthesis. Its core value lies in its rigid, fused ring structure, which serves as a sophisticated scaffold for constructing complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and biotechnology industries who are developing new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral targets.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly protease inhibitors and neurological agents.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the metabolic stability and potency of lead compounds.
• Peptidomimetic Synthesis: The diazabicyclo[3.2.0]heptane core mimics peptide turn structures, making it valuable for creating peptidomimetics in drug discovery.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized APIs under cGMP conditions.

Basic Information

Item	Details
Product Name	6-Boc-2,6-Diazabicyclo[3.2.0]Heptane
CAS No.	1408075-03-5
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl 2,6-diazabicyclo[3.2.0]heptane-6-carboxylate; 6-(tert-Butoxycarbonyl)-2,6-diazabicyclo[3.2.0]heptane; 2,6-Diazabicyclo[3.2.0]heptane, 6-Boc-protected; Bicyclo[3.2.0]heptane-2,6-diamine, N6-Boc derivative; 6-Boc-2,6-diazabicyclo[3.2.0]heptane; (1R,5S)-6-(tert-Butoxycarbonyl)-2,6-diazabicyclo[3.2.0]heptane (for specific stereoisomer); 6-N-Boc-2,6-diazabicyclo[3.2.0]heptane
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure batch-to-batch consistency and high purity for research and cGMP manufacturing applications. Our standard pharmaceutical intermediate grade typically meets a purity specification of ≥97% (by HPLC), with rigorous control of related substances. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity (if applicable), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.