Description

4-(Boc-Aminomethyl)Azepane is a high-purity, protected amine building block of significant importance in modern organic synthesis. This compound matters as a versatile intermediate, enabling the controlled introduction of the azepane scaffold with a protected primary amine functional group, which is crucial for constructing complex molecules. Pharmaceutical researchers and fine chemical manufacturers need it for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those containing the azepane (7-membered nitrogen heterocycle) pharmacophore.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive molecules.
• Peptidomimetic Synthesis: Serves as a constrained scaffold or a side-chain component in the design of peptide mimics to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis or metal complexes.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis organizations (CSOs) producing advanced intermediates for clients in the life sciences sector.

Basic Information

Product Name	4-(Boc-Aminomethyl)Azepane
CAS No.	1408074-78-1
Molecular Formula	C₁₃H₂₆N₂O₂
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-4-(aminomethyl)azepane; tert-Butyl [4-(aminomethyl)azepan-1-yl]carbamate; 4-(Aminomethyl)-N-(tert-butoxycarbonyl)azepane; 1-(tert-Butoxycarbonyl)-4-(aminomethyl)azepane; Azepane-4-methanamine, 1-[(1,1-dimethylethoxy)carbonyl]-; 4-(Boc-aminomethyl)azepane; 4-(Boc-NH-CH₂)-azepane; 1-N-Boc-4-(aminomethyl)azepane
EINECS	Contact for details

Quality Control

Our 4-(Boc-Aminomethyl)Azepane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the Certificate of Analysis. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.