Description

2-(Difluoromethoxy)-1,3-Difluoro-Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique difluoromethoxy and difluoro substitution pattern makes it a valuable precursor for creating complex molecules with tailored electronic and physical properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms can improve efficacy, selectivity, and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a building block for fluorinated liquid crystal compounds and organic electronic materials due to its ability to influence dielectric anisotropy and molecular packing.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, potentially enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Research: A versatile reagent in academic and industrial laboratories for exploring new fluorination methodologies and constructing complex aromatic ethers.

Basic Information

Product Name	2-(Difluoromethoxy)-1,3-Difluoro-Benzene
CAS No.	1404195-17-0
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	1,3-Difluoro-2-(difluoromethoxy)benzene; Benzene, 1,3-difluoro-2-(difluoromethoxy)-; 2-(Difluoromethoxy)-1,3-difluorobenzene; 1,3-Difluoro-2-(difluoromethoxy)benzene; o-(Difluoromethoxy)-1,3-difluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethoxy)-1,3-Difluoro-Benzene is manufactured under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.