Description

1,3-Difluoro-5-(Trifluoromethoxy)Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of fluorine atoms and a trifluoromethoxy group, which are critical for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.

Basic Information

Product Name	1,3-Difluoro-5-(Trifluoromethoxy)Benzene
CAS No.	1404194-50-8
Molecular Formula	C7H3F5O
Molecular Weight	198.09 g/mol
Synonyms	5-(Trifluoromethoxy)-1,3-difluorobenzene; 1,3-Difluoro-5-(trifluoromethoxy)benzene; Benzene, 1,3-difluoro-5-(trifluoromethoxy)-; 3,5-Difluorophenyl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.