Description

n-Cyclopropyl-n-Methylformamide CAS NO 1403483-62-4 is a specialized formamide derivative featuring a cyclopropyl substituent, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure makes it a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This high-purity chemical is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce the cyclopropyl moiety, a privileged scaffold known for influencing metabolic stability and biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclopropyl group enhances biological efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers and functional organic materials with tailored properties.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and probe molecule construction.

Basic Information

Product Name	n-Cyclopropyl-n-Methylformamide
CAS No.	1403483-62-4
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	N-Cyclopropyl-N-methylformamide; N-Methyl-N-cyclopropylformamide; Formamide, N-cyclopropyl-N-methyl-; Cyclopropyl(methyl)amine, N-formyl-; 1-Cyclopropyl-1-methylformamide; N-Cyclopropyl-N-methylcarboxamide; CPMA
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-n-Methylformamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.