Description

Carbamic Acid, n-[(4-Bromo-2,6-Difluorophenyl)Methyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex halogenated aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small-molecule drugs, agrochemicals, and specialty organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides, leveraging its difluorophenyl and bromo substituents.
• Organic Synthesis: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aromatic fragments into target molecules.
• Chemical Biology: Employed as a probe or linker in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or additive in the development of specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	Carbamic Acid, n-[(4-Bromo-2,6-Difluorophenyl)Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	1402673-66-8
Molecular Formula	C13H16BrF2NO2
Molecular Weight	336.18 g/mol
Synonyms	tert-Butyl N-[(4-bromo-2,6-difluorophenyl)methyl]carbamate; N-[(4-Bromo-2,6-difluorophenyl)methyl]carbamic acid tert-butyl ester; tert-Butyl (4-bromo-2,6-difluorobenzyl)carbamate; (4-Bromo-2,6-difluorobenzyl)carbamic acid tert-butyl ester; BOC-4-Bromo-2,6-difluorobenzylamine; 1402673-66-8; Carbamic acid, N-[(4-bromo-2,6-difluorophenyl)methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[(4-Bromo-2,6-Difluorophenyl)Methyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.