Description

2-(4-Cyano-3-(Trifluoromethyl)Phenyl)Acetic Acid is a high-value, multi-functional organic building block featuring both a cyano and a trifluoromethyl group on its aromatic core. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in oncology, inflammation, and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing polar components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Incorporated as a functional monomer to introduce cyano and fluorinated aromatic units into specialty polymers, enhancing their thermal and chemical resistance.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library synthesis.
• Fluorinated Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where fluorine substitution alters light absorption and stability properties.

Basic Information

Product Name	2-(4-Cyano-3-(Trifluoromethyl)Phenyl)Acetic Acid
CAS No.	1402446-14-3
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	[4-Cyano-3-(trifluoromethyl)phenyl]acetic acid; 2-[4-Cyano-3-(trifluoromethyl)phenyl]acetic Acid; α-(4-Cyano-3-trifluoromethylphenyl)acetic Acid; (4-Cyano-3-trifluoromethylphenyl)acetic Acid; 2-(4-Cyano-3-(trifluoromethyl)phenyl)ethanoic Acid; 4-Cyano-3-trifluoromethylphenylacetic Acid; 1402446-14-3
EINECS	Contact for details

Quality Control

Our 2-(4-Cyano-3-(Trifluoromethyl)Phenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.