Description

2,3-Difluoro-4-(Methoxycarbonyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative used as a key synthetic building block in advanced organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and agrochemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity reagent for constructing complex, fluorinated aromatic scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and anti-infective therapies where the difluoro-methoxycarbonyl motif is pharmacologically relevant.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where the introduction of fluorine atoms enhances biological activity, metabolic stability, and environmental profile.
• Material Science & OLED Development: Serves as a building block for fluorinated organic semiconductors, liquid crystals, and light-emitting materials in OLED (Organic Light-Emitting Diode) displays and devices.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical entities in medicinal and synthetic chemistry.
• Ligand & Catalyst Preparation: Can be utilized to synthesize sophisticated ligands for transition metal catalysis or to create novel boron-containing complexes.

Basic Information

Product Name	2,3-Difluoro-4-(Methoxycarbonyl)Phenylboronic Acid
CAS No.	1402238-29-2
Molecular Formula	C9H7BF2O4
Molecular Weight	228.96 g/mol
Synonyms	(2,3-Difluoro-4-(methoxycarbonyl)phenyl)boronic acid; 4-Carbomethoxy-2,3-difluorophenylboronic acid; 2,3-Difluoro-4-methoxycarbonylbenzeneboronic acid; Methyl 2,3-difluoro-4-boronobenzoate; 2,3-Difluoro-4-(methoxycarbonyl)benzeneboronic acid; B-[2,3-Difluoro-4-(methoxycarbonyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-(Methoxycarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.