Description

1-(Difluoromethoxy)-3,5-Difluoro-Benzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique difluoromethoxy and difluoro substitution pattern, which is strategically valuable for modulating the physicochemical properties of target molecules. It is primarily needed by R&D and process development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly where fluorine substitution is used to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for electronic displays, leveraging its aromaticity and fluorine content.
• Organic Electronics: Used in the development of novel materials for organic light-emitting diodes (OLEDs) and semiconductors due to its electronic properties.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of high-performance, fluorinated polymers with enhanced chemical and thermal resistance.

Basic Information

Product Name	1-(Difluoromethoxy)-3,5-Difluoro-Benzene
CAS No.	1400899-01-5
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	3,5-Difluoro-1-(difluoromethoxy)benzene; 3,5-Difluorophenyl difluoromethyl ether; Difluoromethoxy-3,5-difluorobenzene; Benzene, 1-(difluoromethoxy)-3,5-difluoro-; α,α-Difluoro-3,5-difluoroanisole
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethoxy)-3,5-Difluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.