Description

2-(4-Boc-Piperazinyl)-2-(2,4-Dimethoxylphenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a dimethoxyphenyl acetic acid backbone. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric drug discovery pipelines. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where its structural complexity enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Protease Inhibitor Research: Used in the development of novel protease inhibitors due to its specific stereochemistry and functional groups.
• Peptidomimetic Chemistry: Serves as a crucial component in the design and synthesis of peptidomimetics for enhanced drug stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme mechanisms and receptor interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects under cGMP conditions.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry research in both academic laboratories and industrial R&D departments.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(2,4-Dimethoxylphenyl)Acetic Acid
CAS No.	1400644-22-5
Molecular Formula	C21H30N2O7
Molecular Weight	422.47 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(2,4-dimethoxyphenyl)acetic acid; 2-(2,4-Dimethoxyphenyl)-2-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(2,4-dimethoxyphenyl)acetic acid; 2-(2,4-Dimethoxyphenyl)-2-(4-Boc-piperazinyl)acetic acid; Boc-Pip-2,4-Dimethoxyphenylglycine; (2,4-Dimethoxyphenyl)(4-Boc-piperazinyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(2,4-Dimethoxylphenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.