Description

n-Cbz-N'-tert-Butyl-Dl-Phenylglycinamide is a protected amino acid derivative widely used as a key synthetic intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for complex molecule assembly. It is primarily utilized in the pharmaceutical and biotechnology sectors for the research and development of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis for the controlled introduction of phenylglycine analogs with orthogonal protecting groups.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the exploration of novel chemical entities in drug discovery programs.
• Custom Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.
• Bioconjugation: Can be utilized in the development of peptide-drug conjugates and other bioconjugate platforms.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and asymmetric catalysis.

Basic Information

Item	Detail
Product Name	n-Cbz-N'-tert-Butyl-Dl-Phenylglycinamide
CAS No.	1400644-17-8
Molecular Formula	C20H24N2O3
Molecular Weight	340.42 g/mol
Synonyms	Carbobenzoxy-N'-tert-butyl-DL-phenylglycinamide; N-[(Benzyloxy)carbonyl]-N'-(tert-butyl)-DL-phenylglycinamide; Z-N'-t-Bu-DL-Phg-NH2; (RS)-2-[(Benzyloxycarbonyl)amino]-2-phenyl-N-(tert-butyl)acetamide; Benzyl (RS)-(1-[(tert-butylamino)-1-oxo-2-phenylethyl]carbamate; DL-Phenylglycine, N-carboxy-, N-benzyl ester, N'-tert-butylamide
EINECS	Contact for details

Quality Control

Our n-Cbz-N'-tert-Butyl-Dl-Phenylglycinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.