Description

(2R)-1-(Diphenylphosphino)-3-Methyl-2-Butanamine is a chiral, bidentate P,N-ligand of significant importance in asymmetric catalysis. Its value lies in its ability to coordinate with transition metals to form highly selective catalysts, enabling the efficient synthesis of enantiomerically pure compounds. This product is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for applications in asymmetric hydrogenation and C-C bond-forming reactions.

Application

• As a key ligand in asymmetric hydrogenation catalysts for the production of chiral amines and amino acids.
• Utilized in asymmetric C-C coupling reactions, such as Heck and Suzuki reactions, to create chiral intermediates.
• Employed in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Acts as a chiral auxiliary or catalyst in academic and industrial research for novel synthetic methodologies.
• Used in the development of specialty chemicals and advanced materials where stereochemical control is critical.

Basic Information

Product Name	(2R)-1-(Diphenylphosphino)-3-Methyl-2-Butanamine
CAS No.	1400149-69-0
Molecular Formula	C₁₇H₂₂NP
Molecular Weight	271.34 g/mol
Synonyms	(R)-1-(Diphenylphosphino)-3-methyl-2-butanamine; (R)-1-(Diphenylphosphino)-3-methylbutan-2-amine; (2R)-1-(Diphenylphosphanyl)-3-methylbutan-2-amine; (R)-P,N-Ligand; Josiphos-type ligand derivative; Chiral P,N ligand; (R)-DPPB*; (R)-1-(Diphenylphosphino)-2-amino-3-methylbutane
EINECS	Contact for details

Quality Control

Our (2R)-1-(Diphenylphosphino)-3-Methyl-2-Butanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and elemental analysis, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C). Keep the container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.