Description

Piribedil-D8 is a deuterated analog of the dopamine agonist Piribedil, specifically designed for use as an internal standard in analytical chemistry. This high-purity, isotopically labeled compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry and pharmacokinetic studies. It is an essential tool for researchers and quality control laboratories in the pharmaceutical and biotechnology sectors, particularly those focused on neuropharmacology and drug metabolism.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in Liquid Chromatography-Tandem Mass Spectrometry for the precise analysis of Piribedil in biological matrices.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking and quantification of Piribedil and its metabolites in in-vivo and in-vitro studies.
• Bioanalytical Method Development and Validation: Serves as a critical component for developing, validating, and ensuring the robustness of analytical methods in compliance with GLP/GCP guidelines.
• Drug Impurity Profiling and Degradation Studies: Assists in identifying and quantifying process-related impurities or degradation products in active pharmaceutical ingredient (API) batches.
• Forensic and Clinical Toxicology: Supports the accurate measurement of Piribedil levels in forensic analysis and therapeutic drug monitoring.

Basic Information

Product Name	Piribedil-D8
CAS No.	1398044-45-5
Molecular Formula	C16H18D8N4O2
Molecular Weight	306.44 g/mol
Synonyms	Piribedil-d8; 2-[4-(Benzyl)piperazin-1-yl]pyrimidine-d8; 1-(3,4-Methylenedioxybenzyl)-4-(2-pyrimidinyl)piperazine-d8; Trivastal-d8; Pronoran-d8; Dopergin-d8; Piribedil (hexadeutero); Deuterated Piribedil
EINECS	Contact for details

Quality Control

Every batch of Piribedil-D8 is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity, with specifications tailored for use as a certified reference material. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity (by HPLC), isotopic enrichment, and other critical parameters to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.