Description

(3β)-26,27-Dinorcholest-5-En-24-Yne-3,20-Diol CAS NO 1397692-46-4 is a high-purity, synthetic steroid derivative with a modified cholestane backbone. This compound serves as a critical advanced pharmaceutical intermediate and a versatile research chemical for the development of novel therapeutic agents. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Serves as a reference standard or probe in metabolic pathway studies and receptor binding assays.
• Process Development: Employed in scaling up synthetic routes for new chemical entities (NCEs) under GMP conditions.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and steroid chemistry projects.

Basic Information

Product Name	(3β)-26,27-Dinorcholest-5-En-24-Yne-3,20-Diol
CAS No.	1397692-46-4
Molecular Formula	C₂₅H₃₈O₂
Molecular Weight	370.57 g/mol
Synonyms	(3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol; 20,26-Epoxy-27-norcholesterol; 24-Ethynyl-20,26-epoxy-27-norcholest-5-en-3β-ol; 20,26-Epoxy-27-norcholest-5-en-3β-ol-24-yne; 3β,20-Dihydroxy-26,27-dinorcholest-5-en-24-yne; 24-Ethynyl-3β,20-dihydroxy-26,27-dinorcholest-5-ene
EINECS	Contact for details

Quality Control

Our (3β)-26,27-Dinorcholest-5-En-24-Yne-3,20-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.