Description

Fmoc-(Rs)-2-Amino-4-Trityloxybutanoic Acid CAS NO 1396967-68-2 is a protected amino acid derivative, specifically an Fmoc-protected building block with a trityl-protected side chain hydroxyl group. This compound is critical for the synthesis of complex peptides and peptidomimetics, offering orthogonal protection strategies that enable precise, sequential assembly. It is primarily utilized by researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic peptides and investigating structure-activity relationships.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of modified amino acids into peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Design: Essential for creating non-natural peptide analogs with enhanced stability, bioavailability, or biological activity.
• Combinatorial Chemistry Libraries: Serves as a versatile intermediate for generating diverse compound libraries for high-throughput screening.
• Bioconjugation and Probe Development: Useful for synthesizing labeled peptides or peptide conjugates for diagnostic and research applications.
• Academic & Institutional Research: Employed in biochemistry and medicinal chemistry laboratories for fundamental studies on peptide structure and function.

Basic Information

Product Name	Fmoc-(Rs)-2-Amino-4-Trityloxybutanoic Acid
CAS No.	1396967-68-2
Molecular Formula	C42H35NO5
Molecular Weight	633.73 g/mol
Synonyms	Fmoc-DL-2-Amino-4-(triphenylmethoxy)butanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-amino-4-(triphenylmethoxy)butanoic Acid; Fmoc-Asp-OTr-OH (common abbreviation); Fmoc-Asn(Tr)-OH (common abbreviation); 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-(triphenylmethoxy)butanoic Acid; N-Fmoc-2-amino-4-trityloxybutyric Acid; Fmoc-(R,S)-2-Amino-4-(trityloxy)butyric Acid
EINECS	Contact for details

Quality Control

Our Fmoc-(Rs)-2-Amino-4-Trityloxybutanoic Acid is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. We provide comprehensive analytical data, including HPLC purity, chiral purity, and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture (R,S)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.